L-citrulline. The surprising amino acid.

Natural food supplementation useful to counteract sexual disorders and  support physical activity and sports.

L-citrulline, Arginine precursor, improves erections by increasing nitric oxide levels.
In this article you will find how it works and how it can improve sexual well-being, by promoting a better circulation and muscles, organs and tissues oxygenation, throughout the body.

What is L-citrulline

  • L-citrulline, is a nonessential amino acid involved in the urea cycle.
  • It is arginine precursor. Arginine undergoes intense metabolism in the liver and intestines resulting in a reduced absorption and impaired efficacy, reason why its precursor known as L-Citrulline must be administered in oreder to have a therapeutic effect.
  • Taking L- citrulline directly ensures a better bioavailability, higher nitric oxide concentrations, and improved vasodilation.
  • Increases NO levels and improves erectile performance.

Difference between arginine and L-citrulline

L-Citrulline administration results in increase arginine serum concentrations and consequently NO (Nitric Oxide) in a dose-dependent manner. Arginine undergoes intense metabolism in the liver and intestines resulting in reduced ‘absorption and impaired  efficacy. Taking L-CITRULLINE instead of arginine ensures a better substance bio-availability, high nitric oxide concentrations and consequently better vasodilation. If you want to use arginine instead of L-citrulline you would need a considerably more concentration of the substance in order to achieve the same result.

How it acts on muscle level

The increased arginine concentrations given by the administration of L-citrulline and the consequent increase of nitric oxide support the body in a process that naturally occurs : when blood pressure rises excessively, the body reacts by synthesizing nitric oxide; the presence of nitric oxide increases vasodialation by confering a greater supply of oxygenated blood (nutrition) into muscles, and, a consequence of this, you can be physically stronger and improve your muscle mass over time. By ensuring the right amount of the substance to your body will make the difference in both performance and perceived exertion.

Effect on sports performance and recovery

L-citrulline supports the body by the elimination of toxins via urine in a complete way, without leaving toxic and harmful substances in the body for both health and sports performance, with a strong detoxifying action. L-citrulline promotes a metabolic rate increase, supports the body in a better management of the  different active phases interaction that occur during sports activity, as for example, the absorption of food or other ongoing activities by the body, correlating to muscular exertion. During the warm-up, the proper function of nitric oxide-producing processes will contribute to a better exercise. While, during the resting time, the muscle recovery along with  physical-mental wellbeing will be promoted.

L-citrulline supplementation for patients with mild to moderate erectile dysfunction

Clinical test

In January 2011 a clinical trial, conducted on 24 patients with mean age 56.5 ± 9.8 years ,was published in the National Library of Medicine (1) with the aim of testing the efficacy and safety of L-citrulline supplementation in improving erection hardness in patients with erectile dysfunction (ED). The results highlighted that L-citrulline supplementation was safe and well tollerated by patients. The use of L-citrulline, as an alternative treatment for mild to moderate erectile dysfunction, needs further research. All patients who reported an improvement in erection hardness declared to be very satisfied.

Case Report

In January 2011, a case report was published in the National Library of Medicine (2), related to the improvement of erectile dysfunction  that occurs after antidepressants intake even if the patients continued to experience sexual side effects after drug discontinuation. Specifically, a young man suffering from PSSD, such as hypoanesthesia of the genital area, loss of libido, and erectile dysfunction, regained sexual function after 3 months of EDOVIS treatment, a food supplement based on L-citrulline and other commonly used aphrodisiacs.

Dose effects, range of administration, and tolerability

A dose-related study (3)  examined different doses in eight healthy men. Each participant consumed doses of 2, 5, 10 and 15 grams of L-citrulline at separate visits. Even with the highest doses, the participants reported no side effects.
However, the highest doses did not appear to increase arginine in the blood as much as expected, meaning there is a limit to how much of this supplement your body can use. Overall, the study indicated that doses greater than 10 grams are unnecessary.

Conclusions

L-citrulline ensures the best bio-availability of the active ingredeients and an improvment in sports and erectile performance. Take this natural food supplement in order to promote muscle recovery and strengthen the passion. EDOVIS will  successfully enhance your sexual and exercise performance. The optimized 3000mg L-citrulline daily dose (amount already included in EDOVIS) makes the product powerful and complete. EDOVIS is a high-quality product. L-citrulline is generally well tolerated, and gastroenteric reactions occur following disproportionate L-citrulline intake. L-citrulline appears to be safe and there are currently no known side effects and interactions with other known drugs.

EDOVIS TEST.

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